Celiac disease (CD) has a prevalence of nearly 1% of many countries’ populations, and its incidence appears to be increasing.1,2 The risk of CD is elevated among people with a family history,3 and therefore, testing in this population, even among asymptomatic individuals, has been advocated.4,5 However, the frequency with which to test has not been established, and given the possibility of seroconversion and loss of tolerance to gluten during childhood and beyond, repeat testing may be advisable.