Monthly Archives: June 2022
Uncovering 1,058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact
Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing. Continue reading
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Vonoprazan Triple and Dual Therapy for Helicobacter pylori Infection in the US and Europe: Randomized Clinical Trial
Novel, effective treatments for Helicobacter pylori infection are needed. This study evaluated the efficacy of vonoprazan, a potassium-competitive acid blocker, versus standard treatment on H. pylori eradication in the US and Europe. Continue reading
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A MULTICENTER RANDOMIZED CONTROLLED TRIAL OF SURVEILLANCE VERSUS ENDOSCOPIC THERAPY FOR BARRETT’S ESOPHAGUS WITH LOW-GRADE DYSPLASIA: THE SURVENT TRIAL STUDY RATIONALE, METHODOLOGY, INNOVATION AND IMPLICATIONS
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An unusual complication of endoscopic cyanoacrylate Injection for gastric varix
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Splitting Hairs: Folliculin Parts the Good From the Bad in mTORC1 Control Over Lipid Metabolism
Gosis BS, Wada S, Thorsheim C, et al. Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1. Science 2022;376(6590):eabf8271. Continue reading
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The Influence of Place and Geography on Outcomes Across the Cancer Continuum
As a leading cause of morbidity and mortality in the United States, gastrointestinal (GI) cancers are diagnosed in 340,000 people and account for nearly 170,000 cancer-related deaths each year.1 Incidence and mortality rates of many GI cancers, includi… Continue reading
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Bile duct stricture at the superior margin of pancreas
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Target sign and abdominal pain, an approach to diagnosis and treatment
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The global landscape of esophageal squamous cell carcinoma and esophageal adenocarcinoma incidence and mortality in 2020 and projections to 2040: New estimates from GLOBOCAN 2020
To provide an overview of the burden of esophageal cancer in 185 countries in 2020 and projections for the year 2040. Continue reading
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Rear Window—What Can the Gut Tell Us About Long-COVID?
While life-threatening acute coronavirus disease 2019 (COVID-19) is mostly linked to respiratory insufficiency or exacerbation of underlying comorbidity, up to 50% of patients with acute COVID-19 may experience mild to moderate gastrointestinal symptom… Continue reading
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