Monthly Archives: June 2022

Unusual White Esophageal Patches with Cobblestone Appearance

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A Trapped Colon

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An 80-Year-Old Man with Hematochezia and Hyperkalemia

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Hide and Seek – Dysplasia Camouflage in a Patient with Barrett’s Esophagus

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Rate of autoactivation determines pancreatitis phenotype in trypsinogen mutant mice

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Prolonging Survival in Advanced Esophageal Squamous Cell Carcinoma With Immune Checkpoint Inhibitors

Doki Y, Ajani A, Xu L, et al. Nivolumab combination therapy in advanced esophageal squamous-cell carcinoma. N Engl J Med 2022;386:449–462. Continue reading

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Food Insecurity in Digestive Diseases

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Can We Predict the Onset of Celiac Disease?

Celiac disease (CD) has a prevalence of nearly 1% of many countries’ populations, and its incidence appears to be increasing.1,2 The risk of CD is elevated among people with a family history,3 and therefore, testing in this population, even among asymp… Continue reading

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β-Catenin Is a Novel Target in YES-associated Protein–Driven Cholangiocarcinoma

Cholangiocarcinoma (CCA) is a heterogeneous and devastating type of cancer that develops from biliary cells in the biliary tract. Among the different subtypes of CCA, intrahepatic CCA (iCCA) accounts for 15% of primary liver tumors and has become a gro… Continue reading

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Arid1a: A Gatekeeper in the Development of Pancreatic Cancer From a Rare Precursor Lesion

Pancreatic intraepithelial neoplasia, intraductal pancreatic mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) are the common precursor lesions of pancreatic cancer. The gene abnormalities of those precursor lesions are characterized by Kras… Continue reading

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