Acute pancreatitis (AP) is associated with significant morbidity and mortality.1 The short-term outcomes in AP are determined both by systemic and local complications. Persistent organ failure, which defines the severity of AP, leads to a high mortality of up to 30%–40%.1–3 Among the local complications of AP, infected necrotizing pancreatitis (INP) is the most sinister. The treatment of INP has undergone a sea change over the past 2 decades moving away from the dogma of “open” surgical necrosectomy to “a conservative-first” step-up approach starting with antibiotics, drainage, and scaling up to minimally invasive necrosectomy, which can be achieved either through endoscopic, laparoscopic or video-assisted retroperitoneal debridement technique.