Monthly Archives: July 2022
An Unusual Cause of Intractable Hiccup and Intermittent Low Fever
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AGA Clinical Practice Update: Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Lean Individuals: Expert Review
Nonalcoholic fatty liver disease (NAFLD) is well recognized as a leading etiology for chronic liver disease, affecting >25% of the US and global populations. Up to 1 in 4 individuals with NAFLD have nonalcoholic steatohepatitis, which is associated wit… Continue reading
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Disclosure and Reflection After an Adverse Event: Tips for Training and Practice
A 73-year-old woman with hypertension and hypothyroidism undergoes a surveillance colonoscopy for a history of nonadvanced adenomas. Her last colonoscopy was 5 years ago where 5 small tubular adenomas were removed with cold snare. A third-year gastroen… Continue reading
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Biogeographic variation and functional pathways of the gut microbiota in celiac disease
Genes and gluten are necessary but insufficient to cause celiac disease (CeD). Altered gut microbiota has been implicated as an additional risk factor. Variability in sampling site may confound interpretation and mechanistic insight, as CeD affects pri… Continue reading
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Long-term Outcomes after Endoscopic Submucosal Dissection for Large Colorectal Epithelial Neoplasms: A Prospective, Multicenter, Cohort Trial from Japan
To determine the long-term outcomes after colorectal endoscopic submucosal dissection (ESD), we conducted a large, multicenter, prospective cohort trial with a 5-year observation period. Continue reading
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Regulatory and Clinical Expert Perspective of the 2022 FDA Draft Guidance: Celiac Disease: Developing Drugs for Adjunctive Treatment to a Gluten-Free Diet
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Novel, Emerging Risk Factors for Colorectal Cancer Remain Understudied
For more than 3 decades, colorectal cancer (CRC) incidence rates have been increasing rapidly among adults Continue reading
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Using Human Induced Pluripotent Stem Cell Derived Organoids to Identify New Pathologies in Patients with PDX1 Mutations
Two patients with homozygous mutations in PDX1 presented with pancreatic agenesis, chronic diarrhea and poor weight gain, the causes of which were not identified through routine clinical testing. We aim to perform a deep analysis of the stomach and int… Continue reading
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Treatment of IBS Using FMT: A Step Forward?
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Failure to Achieve Target Drug Concentrations During Induction and Not HLA-DQA1*05 Carriage is Associated with Anti-Drug Antibody Formation in Patients with Inflammatory Bowel Disease: HLA-DQA1*05 Testing for Immunogenicity to anti-TNF Remains Relevant in IBD, But Depends on Therapeutic Drug Monitoring Strategy
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