Monthly Archives: August 2022
A Growing Hope for Earlier Detection of Pancreatic Cancer
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Risankizumab for Induction and Maintenance of Remission in Crohn’s Disease
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Gastroplasty with Endoscopic Myotomy (GEM) for the Treatment of Obesity: Preliminary Efficacy and Physiologic Results
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Targeting de novo lipogenesis by different approaches shows promise in non-alcoholic steatohepatitis
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Clinical manifestations and stool load of atypical enteropathogenic E. coli infections in U.S. children and adults.
There is debate whether atypical enteropathogenic E. coli (aEPEC) causes disease in adults. aEPEC is commonly detected in symptomatic and asymptomatic individuals. aEPEC, in contrast to typical EPEC, lacks bundle forming pili, altering its pathogenicit… Continue reading
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Combined MEK and STAT3 inhibition uncovers stromal plasticity by enriching for cancer-associated fibroblasts with mesenchymal stem cell-like features to overcome immunotherapy resistance in pancreatic cancer
We have shown that reciprocally activated RAS/MEK and JAK/STAT3 pathways mediate therapeutic resistance in pancreatic ductal adenocarcinoma (PDAC), while combined MEK and STAT3 inhibition (MEKi+STAT3i) overcomes such resistance and alters stromal archi… Continue reading
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The rising burden of inflammatory bowel disease in Denmark over two decades: a nationwide cohort study
Shifts in epidemiological stages of inflammatory bowel disease (IBD) carry implications towards understanding IBD etiology and managing clinical care. We conducted a temporal analysis of the epidemiology of IBD between 1995 and 2016 in the Danish natio… Continue reading
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Needle-free NAFLD prognostication: Moving One Step Closer
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Effect of 5-hydroxytryptophan on fatigue in quiescent inflammatory bowel disease: a randomized controlled trial
Fatigue is highly prevalent among patients suffering from inflammatory bowel disease (IBD) and only limited treatment options are available. Based on the hypothetical link between low serum tryptophan concentrations and fatigue, we determined the effec… Continue reading
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A Rare Cause of Dysphagia: Diagnosis and Treatment
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