Daily Archives: November 16, 2022
Loss of SUV420H2-dependent chromatin compaction drives right-sided colon cancer progression
Epigenetic processes regulating gene expression contribute markedly to epithelial cell plasticity in colorectal carcinogenesis. The lysine methyltransferase SUV420H2 comprises an important regulator of epithelial plasticity and is primarily responsible… Continue reading
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N-glycosylation regulates intrinsic IFN-γ resistance in colorectal cancer: implications for immunotherapy.
Advanced colorectal carcinoma (CRC) is characterized by a high frequency of primary immune evasion and refractoriness to immunotherapy. Given the importance of IFN-γ in CRC immunosurveillance, we investigated whether and how acquired IFN-γ resistance i… Continue reading
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The Case for FLIP Panometry in Clinical Practice
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