Daily Archives: November 18, 2022

Shining a Light on Barrier Function

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Promote or prevent? Gut microbial function and immune status may determine the effect of fiber in IBD

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Dysregulated amino acid sensing drives colorectal cancer growth and metabolic reprogramming leading to chemoresistance.

CRC is a devastating disease highly modulated by dietary nutrients. mTORC1 contributes to tumor growth and limits therapy responses. Growth factor signaling is a major mechanism of mTORC1 activation. However, compensatory pathways exist to sustain mTOR… Continue reading

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