Daily Archives: February 3, 2023
Reply: application of administrative data towards epidemiological research
Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer (HDGC) is a dominantly-inherited cancer syndrome characterized by a high incidence of diffuse gastric cancer (DGC) and lobular breast cancer (LBC). HDGC is caused by germline mutations in two genes involved in the epit… Continue reading
Surveillance in Barrett’s Esophagus: Challenges, Progress and Possibilities
Endoscopic surveillance of Barrett’s esophagus (BE), aiming to detect prevalent dysplasia and adenocarcinoma, followed by effective endoscopic treatment, is an integral part of the esophageal adenocarcinoma (EAC) prevention paradigm. However, several l… Continue reading
SOX9 modulates the transformation of gastric stem cells through biased symmetric cell division
Transformation of stem/progenitor cells has been associated with tumorigenesis in multiple tissues, but in the stomach stem cells have been hard to localize. We therefore aimed to use a combination of several markers in order to better target oncogenes… Continue reading