Daily Archives: February 20, 2023

Hydroxyphenylpyruvate dioxygenase is a metabolic immune checkpoint for UTX-deficient colorectal cancer

Posted on February 20, 2023 by Gastroenterology Journal

Aberrant epigenetic events mediated by histone methyltransferases and demethylases contributes to malignant progression of colorectal cancer (CRC). However, the role of the histone demethylase ubiquitously transcribed tetratricopeptide repeat on chromo… Continue reading →

Posted in News | Comments Off on Hydroxyphenylpyruvate dioxygenase is a metabolic immune checkpoint for UTX-deficient colorectal cancer

Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation

Posted on February 20, 2023 by Gastroenterology Journal

Despite therapeutic advances, effective treatments for chronic constipation remain an unmet need. The vibrating capsule is a non-pharmacologic, orally-ingested, programmable capsule that vibrates intraluminally to induce bowel movements. We aimed to de… Continue reading →

Posted in News | Comments Off on Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation