Daily Archives: February 24, 2023

Targeting UBE2T potentiates gemcitabine efficacy in pancreatic cancer by regulating pyrimidine metabolism and replication stress

Although small patient subsets benefit from current targeted strategies or immunotherapy, gemcitabine remains the first-line drug for pancreatic cancer (PC) treatment. However, gemcitabine resistance is widespread and compromises long-term survival. He… Continue reading

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Table of Contents

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Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using “Best Case/Worst Case”

There are emerging data revealing disparities in serious illness care for patients with advanced liver disease. Although liver disease is the 11th leading cause of death overall in adults in the United States, it is the 4th and 7th leading cause of dea… Continue reading

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Elsewhere in The AGA Journals (Preview Section)

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Editorial Board

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