Monthly Archives: February 2023
The Gut Microbial Bile Acid Modulation and its Relevance to Digestive Health and Diseases
The human gut microbiome has been linked to numerous digestive disorders, but its metabolic products have been much less well characterized, in part due to the expense of untargeted metabolomics and in part to the lack of ability to process the data. I… Continue reading
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Comparing time to diagnosis and treatment between younger and older adults with colorectal cancer: A population-based study
Younger adults ( Continue reading
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Hydroxyphenylpyruvate dioxygenase is a metabolic immune checkpoint for UTX-deficient colorectal cancer
Aberrant epigenetic events mediated by histone methyltransferases and demethylases contributes to malignant progression of colorectal cancer (CRC). However, the role of the histone demethylase ubiquitously transcribed tetratricopeptide repeat on chromo… Continue reading
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Randomized Placebo-Controlled Phase 3 Trial of Vibrating Capsule for Chronic Constipation
Despite therapeutic advances, effective treatments for chronic constipation remain an unmet need. The vibrating capsule is a non-pharmacologic, orally-ingested, programmable capsule that vibrates intraluminally to induce bowel movements. We aimed to de… Continue reading
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An Overlooked Cause of Multiple Liver Nodules Exhibiting the Bull’s-Eye Sign
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Pancreatic Cancer: Changing Epidemiology and New Approaches to Risk assessment, Early Detection, and Prevention
Pancreatic cancer usually results in poor survival with limited options for treatment, as most affected individuals present with advanced disease. Early detection of pre-invasive pancreatic neoplasia and identifying molecular therapeutic targets provid… Continue reading
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Esophageal laceration with uncertain cause
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Correction
Maringhini A, Maringhini M. Bile and Liver in Pregnancy: No One Split Apart What God Has Joined Together. Gastroenterology 2023;164:310–311. Continue reading
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RNA Sequencing Identifies Frequent Mitogen Activated Protein Kinase-Associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas
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Drug-Induced Liver Injury with Ritonavir-Boosted Nirmatrelvir: Evidence from COVID-19 EUA Adverse Event Reporting System
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