Daily Archives: March 10, 2023
A “two-in-one hit” model of shortcut carcinogenesis in MLH1 Lynch syndrome carriers
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The efficacy of peroral endoscopic myotomy vs. pneumatic dilation as treatment for patients with achalasia suffering from persistent or recurrent symptoms after laparoscopic Heller myotomy. A RANDOMIZED CLINICAL TRIAL
For achalasia patients with persistent or recurrent symptoms after laparoscopic Heller myotomy (LHM), pneumatic dilation (PD) is the most frequently used treatment. Per-oral endoscopic myotomy (POEM) is increasingly being investigated as rescue therapy… Continue reading
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BMPR2 as a novel predisposition gene for hereditary colorectal polyposis
Colorectal cancer (CRC) is one of the most prevalent tumours worldwide, with incidences (particularly in the context of early-onset cases) quickly increasing despite important prevention efforts, mainly in the form of population-wide screening programm… Continue reading
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A TEAD2-driven endothelial-like program shapes basal-like differentiation and metastasis of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDA), with its highly metastatic propensity, is one of the most lethal subtypes of pancreatic cancer. Although recent large-scale transcriptomic studies have demonstrated that heterogeneous gene expressions play an ess… Continue reading
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