Daily Archives: May 9, 2023

ALKBH5 Drives Immune Suppression via targeting AXIN2 to Promote Colorectal Cancer and is a Target for Boosting Immunotherapy

Posted on May 9, 2023 by Gastroenterology Journal

Immune checkpoint blockade (ICB) therapy only benefits a small subset of colorectal cancer (CRC) patients and identification of CRC-intrinsic events modulating ICB efficacy is an unmet need. Here, we revealed AlkB Homolog 5 (ALKBH5), an RNA N6-methylad… Continue reading →

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