Question: An 85-year-old female patient with a history of chronic lumbar pain and short segment Barrett’s esophagus, was referred to our endoscopy department after a protracted episode of fatigue, which was attributed to iron deficiency anemia (hemoglobin concentration 6.8 g/dL; reference range, 12.0–16.0 g/dL). No external signs of bleeding were detected. Upper gastrointestinal endoscopy showed a relatively short tongue of Barrett’s esophagus (C0M2) and a clean based antral ulcer of approximately 5 mm in diameter.