Sweat based wearable sensors have shown a lot of promise in the recent years due to the ability of tracking the biomarkers in real-time. Among the various biomarkers present in sweat, cytokine concentrations have been shown in comparable range to the blood cytokines. Detection of sweat cytokines can help in monitoring of inflammation in real-time. In this work, we demonstrate a duplex cytokine sweat based sensor for real-time monitoring. The developed sensor can detect interleukin-6 (IL-6) and interleukin-10 (IL-10) in real-time that can aid in prognosis or recovery of inflammation.