ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice

Posted on March 11, 2020 by Gastroenterology Journal

We identified a protein that is upregulated in human HCC samples. When we deleted or inhibited this protein in mice, liver tumors grew more slowly and the mice had longer survival times.

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