Protective Actions of Epithelial 5-hydroxytryptamine 4 Receptors in Normal and Inflamed Colon

The 5-hydroxytryptamine receptor 4 (5-HT4R or HTR4) is expressed in the colonic epithelium but little is known about its functions there. We examined whether activation of colonic epithelial 5-HT4R protects colons of mice from inflammation.

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