Squalene epoxidase (SQLE) is the rate-limiting enzyme for cholesterol biosynthesis. We elucidated the functional significance, molecular mechanisms and clinical impact of SQLE in non-alcoholic steatohepatitis (NASH).
Squalene epoxidase (SQLE) is the rate-limiting enzyme for cholesterol biosynthesis. We elucidated the functional significance, molecular mechanisms and clinical impact of SQLE in non-alcoholic steatohepatitis (NASH).