Epithelia-sensory neuron crosstalk underlies cholestatic itch induced by lysophosphatidylcholine

Posted on April 2, 2021 by Gastroenterology Journal

Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of anti-pruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus.

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