Pancreatic ductal adenocarcinoma (PDAC) remains a major challenge in cancer medicine. Given the increase in incidence and mortality, interdisciplinary research is necessary to translate basic knowledge into therapeutic strategies improving the outcome of patients. On the 4th and 5th of February 2021, three German pancreatic cancer research centers, the clinical research unit (CRU) 5002 from Göttingen, the collaborative research center (CRC) 1321 from Munich, and CRU325 from Marburg organized the 1st Virtual Göttingen-Munich-Marburg Pancreatic Cancer Meeting in order to foster scientific exchange.