Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease is a comprehensive review of the use of anti-tumor necrosis factor (TNF) therapy in patients with inflammatory bowel disease (IBD). The book includes a preface and 35 chapters, which can be broken down into 5 major sections. The first section highlights the science behind anti-TNF therapy, including the physiologic role of TNF in mucosal immunology, the pathophysiologic role of TNF in IBD, and the mechanism of action of anti-TNF therapy.