LACTOCOCCUS LACTIS DELIVERY OF SURFACE LAYER PROTEIN A PROTECTS MICE FROM COLITIS BY RE-SETTING HOST IMMUNE REPERTOIRE

Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation comprised of Crohn’s disease and ulcerative colitis. Centers for Disease Control and Prevention report that 1.3% of the population of the United States (approximately 3 million people) were affected by the disease in 2015, and the number keeps increasing over time. IBD has a multifactorial etiology, from genetic to environmental factors. Most of the IBD treatments revolve around disease management, by reducing the inflammatory signals.

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