NOTCH-YAP1/TEAD-DNMT1 axis drives hepatocyte reprogramming into intrahepatic cholangiocarcinoma

Posted on May 9, 2022 by Gastroenterology Journal

We identify a subset of intrahepatic bile duct cancers to originate from hepatocytes instead of bile duct cells, and identify the epigenetic molecular basis of this fatal disease.

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