Question: A 75-year-old woman with a history of chronic obstructive lung disease, alcoholic cirrhosis, and a recent episode of polymicrobial bacteremia (Enterococcus avium and Bacteroides) at an outside hospital 2 months before presentation was admitted with shortness of breath and abdominal pain. Blood cultures on hospital day 1 demonstrated vancomycin-resistant enterococcus bacteremia. She was placed on daptomycin but developed hypotension, oliguria, and altered mental status. She was diagnosed with septic shock.