Question: A 73-year-old male underwent screening colonoscopy. He has lived for a couple of years in Namibia on his farm and has gone several times on hunting safaris in other African countries. He was not aware of any serious diseases in the past except for fever for 2–3 days and a rash on his back and chest during one of his safaris in Zambia. Colonoscopy was performed on an outpatient basis and documented normal findings except for a 2-cm mass in the distal sigmoid with a normal-appearing mucosa on narrow band imaging (Figure A, B).