Author Archives: Andrew T. Chan, Christopher S. Williams

In a large cohort of an average-risk population undergoing colorectal cancer screening using fecal immunochemical testing, an increased fecal hemoglobin concentration was associated with a higher risk of subsequent colorectal advanced neoplasia. Continue reading →

In a large cohort of patients with chronic hepatitis C infection, sustained virologic response after direct-acting antiviral therapy lowered, but did not eliminate, the risk of hepatocellular carcinoma. Continue reading →

In a cohort of obese Latino and African American children, 9 days of isocaloric restriction decreased liver fat, visceral fat, and de novo lipogenesis, and improved insulin kinetics. Continue reading →

In a cohort of obese Latino and African American children, 9 days of isocaloric restriction decreased liver fat, visceral fat, and de novo lipogenesis, and improved insulin kinetics. Continue reading →

In an analysis of data from a pilot screening program, 23% of colorectal cancers were interval cancers after fecal immunochemical testing. Continue reading →

In a small study of patients with esophagitis or Barrett’s esophagus, a weight-lifter belt increased postprandial gastroesophageal reflux. Continue reading →

In a study of 138 treatment-naïve pediatric inflammatory bowel disease patients and 49 controls, rectal expression of type 2 and type 17 immune response genes discriminated ulcerative colitis from Crohn’s colitis and was associated with clinical out… Continue reading →

A novel, fluorescently labeled peptide topically administered to the proximal colon distinguished sessile serrated adenomas from normal colonic mucosa with 89% sensitivity and 92% specificity in a small trial. Continue reading →

In a multicenter, randomized, double-blind, placebo-controlled, parallel group trial, budesonide oral suspension improved symptomatic, endoscopic, and histologic outcomes in patients with symptomatic eosinophilic esophagitis. Continue reading →

In a randomized controlled trial of children in the Netherlands with functional constipation, pelvic physiotherapy was more effective than standard medical care in relieving constipation after 6 months of follow-up. Continue reading →