Author Archives: Gastroenterology Journal

In Memoriam: Tadataka “Tachi” Yamada, MD, 1945–2021

The gastroenterology community mourns the loss of Tadataka “Tachi” Yamada, who passed away on August 4, 2021, at the age of 76 years. He is survived by Leslie, his beloved wife of 54 years; his children, Sanae and Takeo, and their spouses; his 4 grandc… Continue reading

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How to Succeed in Digestive Research

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A Middle-aged Patient with a prolapsing rectal mass

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An unexpected guest in a patient with ulcerative colitis

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Adding Fuel to The Fire? A Role of Intraepithelial Lymphocytes in Enteric Immune Responses to SARS-CoV-2 Infection

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Positioning infliximab and vedolizumab in the treatment of moderate-to-severe ulcerative colitis

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Safety and Efficacy of Anti-TNF Therapy in Older Adults with Ulcerative Colitis: A New Path Forward

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The different immune profiles of normal colonic mucosa in cancer-free Lynch syndrome carriers and Lynch syndrome colorectal cancer patients

Due to the high load of immunogenic frameshift neoantigens, tumors arising in individuals with Lynch syndrome (LS), the most common inherited colorectal cancer (CRC) syndrome, are characterized by a pronounced immune infiltration. However, the immune s… Continue reading

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γδ intraepithelial lymphocytes facilitate pathological epithelial cell shedding via CD103-mediated granzyme release.

Excessive shedding of apoptotic enterocytes into the intestinal lumen is observed in inflammatory bowel disease and is correlated with disease relapse. Based on their cytolytic capacity and surveillance behavior, we investigated whether intraepithelial… Continue reading

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Air-Fluid Level in the Right Hemithorax: A Case Hard to Stomach

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