Author Archives: Gastroenterology Journal
In Memoriam: Tadataka “Tachi” Yamada, MD, 1945–2021
The gastroenterology community mourns the loss of Tadataka “Tachi” Yamada, who passed away on August 4, 2021, at the age of 76 years. He is survived by Leslie, his beloved wife of 54 years; his children, Sanae and Takeo, and their spouses; his 4 grandc… Continue reading
How to Succeed in Digestive Research
A Middle-aged Patient with a prolapsing rectal mass
An unexpected guest in a patient with ulcerative colitis
Adding Fuel to The Fire? A Role of Intraepithelial Lymphocytes in Enteric Immune Responses to SARS-CoV-2 Infection
Positioning infliximab and vedolizumab in the treatment of moderate-to-severe ulcerative colitis
Safety and Efficacy of Anti-TNF Therapy in Older Adults with Ulcerative Colitis: A New Path Forward
The different immune profiles of normal colonic mucosa in cancer-free Lynch syndrome carriers and Lynch syndrome colorectal cancer patients
Due to the high load of immunogenic frameshift neoantigens, tumors arising in individuals with Lynch syndrome (LS), the most common inherited colorectal cancer (CRC) syndrome, are characterized by a pronounced immune infiltration. However, the immune s… Continue reading
γδ intraepithelial lymphocytes facilitate pathological epithelial cell shedding via CD103-mediated granzyme release.
Excessive shedding of apoptotic enterocytes into the intestinal lumen is observed in inflammatory bowel disease and is correlated with disease relapse. Based on their cytolytic capacity and surveillance behavior, we investigated whether intraepithelial… Continue reading