Author Archives: Gastroenterology Journal

Because inflammatory bowel disease is increasing worldwide and can lead to colitis-associated carcinoma (CAC), new interventions are needed. We have shown that spermine oxidase (SMOX), which generates spermidine (Spd), regulates colitis. Here we determ… Continue reading →

Functional cure, defined by hepatitis B surface antigen (HBsAg) loss, is rare during nucleos(t)ide analogue (NA) therapy and guidelines on finite NA therapy have not been well established. We aim to analyze off-therapy outcomes following NA cessation i… Continue reading →

Mirikizumab is a humanized monoclonal antibody targeting IL-23p19 with demonstrated efficacy in psoriasis and ulcerative colitis. We investigated the safety and efficacy of mirikizumab in patients with moderate-to-severe Crohn’s disease (CD). Continue reading →

Gastroenterologists spend much of their working lives focused on cancer prevention through an array of approaches, including screening and surveillance colonoscopy, endoscopic surveillance of Barrett’s esophagus, investigating pancreatic cysts noted in… Continue reading →

Inequities in multiple dimensions are pervasive across groups and intersections of race, sex, sexual orientation, gender identity, geography, and others stratifications in society.1–7 The disproportionate effect of COVID-19 on racial and ethnic minorit… Continue reading →