Author Archives: Gastroenterology Journal
“Going the extra mile”: A Sox10 target, Cdh19, is Required for Sacral NC Migration in ENS Development
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Single Cell DNA Sequencing Reveals Chromosomal Diversity in HCC and a Novel Model of HCC Evolution
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Epidemiology, etiology and treatment of gastroparesis: real-world evidence from a large US national claims database
While gastroparesis carries a considerable healthcare and patient burden, associated epidemiological data are limited. To provide new real-world evidence for gastroparesis, we estimated disease prevalence, and investigated patient demographics and dise… Continue reading
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Cyclooxygenases and Prostaglandins in Tumor Immunology and Microenvironment of Gastrointestinal Cancer
Chronic inflammation is a known risk factor for gastrointestinal cancer. The evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) suppress the incidence, growth, and metastasis of gastrointestinal cancer supports the concept that an NSAID target… Continue reading
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Transferable IgA-coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation
Fecal microbiota transplantation (FMT) is an emerging treatment modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy for FMT in the treatment of UC, but a better understanding of the transferable microbiota and… Continue reading
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In Memoriam: Michael N. Marsh, BTh, DPhil, DM, DSc, FRCP
With personal regret, we note the death of Professor Michael N. Marsh. For more than 50 years, the name Marsh has dominated not only the world of celiac disease but additionally the fields of intestinal morphology and immunopathology, promoting the acc… Continue reading
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Epithelial XBP1 coordinates TP53-driven DNA damage responses and suppression of intestinal carcinogenesis
Welz et al. show that XBP1 coordinates epithelial stem cell function in response to DNA damage in a mechanism involving the tumor suppressor TP53. Continue reading
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Serologic response to coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis
Patients with immune-mediated inflammatory diseases (IMIDs) have an increased risk of COVID-19, primarily attributed to the use of immunosuppressive drugs such as glucocorticoids, which may attenuate the response to vaccines. This meta-analysis aims to… Continue reading
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Epithelium Replacement Contributes to Field Expansion of Squamous Epithelium and Ulcerative Colitis-Associated Neoplasia
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Fevers, acute hepatitis, and hypercoagulability in an immunocompetent host
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