Author Archives: Gastroenterology Journal

A novel role of circular RNA in intestinal epithelial repair

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Systemic inflammation in pre-clinical ulcerative colitis

Pre-clinical ulcerative colitis is poorly defined. We aimed to characterize the pre-clinical systemic inflammation in ulcerative colitis, using a comprehensive set of proteins. Continue reading

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A Most Unusual Polyposis

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Liver-resident bystander CD8+ T cells contribute to liver disease pathogenesis in chronic hepatitis D virus infection

The hepatitis D virus (HDV) causes the most severe form of chronic hepatitis, often progressing to cirrhosis within 5-10 years. There is no curative treatment and the mechanisms underlying the accelerated liver disease progression are unknown. Continue reading

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Anti-microbial antibody response is associated with future onset of Crohn’s disease independent of biomarkers of altered gut barrier function, subclinical inflammation, and genetic risk

/Aim: Altered host immune reactivity to microbial antigens is hypothesized to trigger the onset of Crohn’s disease (CD). We aimed to assess whether increased serum anti-microbial antibody response in asymptomatic first-degree relatives (FDR) of CD pati… Continue reading

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Comparison of culture with antibiogram to NGS using bacterial isolates and formalin fixed paraffin embedded gastric biopsies

The decline in Helicobacter pylori cure rates emphasizes the need for readily available methods to determine antimicrobial susceptibility. Continue reading

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An Unusual and Unexpected Post-Esophagectomy Complication

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Serial ctDNA detection using a personalized, tumor-informed assay in esophageal adenocarcinoma patients following resection

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Outcomes of SARS-CoV-2 Infection in Patients with Chronic Liver Disease and Cirrhosis: a N3C Study

In chronic liver disease (CLD) patients with or without cirrhosis, existing studies on the outcomes with SARS-CoV-2 infection have limited generalizability. We used the National COVID Cohort Collaborative (N3C), a harmonized electronic health record (E… Continue reading

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Covering the Cover

Specific carbohydrate diet was not superior to Mediterranean diet in achieving symptomatic remission or biological response in adults with Crohn’s disease Continue reading

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