Author Archives: Gastroenterology Journal

WFDC2 promotes spasmolytic polypeptide-expressing metaplasia through the upregulation of IL33 in response to injury

WAP four-disulfide core domain protein 2 (WFDC2), also known as human epididymis protein 4 (HE4), is a small secretory protein that is highly expressed in fibrosis and human cancers, particularly in the ovaries, lungs, and stomach. However, the role of… Continue reading

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Recurrent Epistaxis and Diffuse Hepatic and Splenic Vascular Malformations

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A visual engram worth remembering

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Tumor-specific delivery of 5FU-incorporated EGFR-targeted aptamers as an efficient treatment in pancreatic ductal adenocarcinoma models

Fluoropyrimidine 5-fluorouracil (5FU) increasingly represents the chemotherapeutic backbone for neoadjuvant, adjuvant and palliative treatment of pancreatic ductal adenocarcinoma (PDAC). Even in combination with other agents, 5FU efficacy remains trans… Continue reading

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Bariatric surgery and cancer risk in NAFLD – Effective intervention for a select few

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Hybrid stomach-intestinal chromatin states underlie human Barrett’s metaplasia

Tissue metaplasia is uncommon in adults because established cis-element programs resist rewiring. In Barrett’s esophagus, the distal esophageal mucosa acquires predominantly intestinal character, with notable gastric features, and is predisposed to dev… Continue reading

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Residual gastrointestinal symptoms after fecal microbiota transplantation for Clostridioides difficile infection: a matter of efficacy rather than safety?

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Novel Orally Formulated Mixed Micelles Optimize Vitamin K Absorption Under Bile Deficient Conditions

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In Memoriam, David A. Ahlquist, M.D.

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The colorectal cancer lipidome: Is there any differences of lipid species between right and left colorectal cancers?

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