Author Archives: Gastroenterology Journal
Deciphering the “Sausage” Pancreas
Fever and abdominal pain in acute pancreatitis
Genetic and epigenetic characteristics of inflammatory bowel disease associated colorectal cancer
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder associated with an elevated risk of colorectal cancer (CRC). IBD-associated CRC (IBD-CRC) may represent a distinct pathway of tumorigenesis compared to sporadic CRC (sCRC). O… Continue reading
Sugary truth of early-onset colorectal neoplasia – not so sweet after all
Does Fatherhood Matter? Preconception Use of Biologics and Immunomodulators by Fathers With Immune-Mediated Diseases and Birth Outcomes of Their Offspring
Artificial Intelligence for the Evaluation of Mucosal Healing in IBD: The Future is Here
MondoA-TXNIP axis maintains regulatory T cell identity and function in colorectal cancer microenvironment
The metabolic features and function of intratumoral Tregs are ambiguous in colorectal cancer. Tumor-infiltrating Tregs are reprogrammed to exhibit high glucose-depleting properties and adapt to the glucose-restricted microenvironment. The glucose-respo… Continue reading
Colonic Motility is Improved by the Activation of 5-HT2B Receptors on Interstitial Cells of Cajal in Diabetic Mice
Constipation is commonly associated with diabetes. Serotonin (5-HT), produced predominantly by enterochromaffin (EC) cells via tryptophan hydroxylase 1 (TPH1), is a key modulator of gastrointestinal (GI) motility. However, the role of serotonergic sign… Continue reading
A diffusion-like process accommodates new crypts during clonal expansion in human colonic epithelium
Colorectal cancer (CRC) is thought to arise when the cumulative mutational burden within colonic crypts exceeds a certain threshold that leads to clonal expansion and ultimately neoplastic transformation. Therefore, quantification of the fixation and s… Continue reading
Non-food prebiotic, probiotic, and synbiotic use has increased in U.S. adults and children from 1999 to 2018
Public interest in pre- , pro-, and synbiotic products is increasing because of interactions between gut microbiota and human health. Our aim was to describe non-food (from dietary supplements or medication) pre, pro-, and synbiotic use by U.S. adults … Continue reading