Author Archives: Gastroenterology Journal
Defining interactions between the genome, epigenome, and the environment in inflammatory bowel disease: progress and prospects
Recent advances in our understanding of the pathogenesis of inflammatory bowel disease (IBD) have highlighted the complex interplay between the genome, epigenome and the environment. Despite of the exciting advances in genomics that have enabled the id… Continue reading
Over-the-Scope Clips in the Initial Endoscopic Treatment of Nonvariceal Upper Gastrointestinal Bleeding: Ready for Prime Time?
Alcohol minimum unit pricing reduces alcohol-specific hospitalizations and deaths.
“Enhancing Nutrition and Obesity Education in GI Fellowship through Universal Curriculum Development”
Distinct serum immune profiles define the spectrum of acute and chronic pancreatitis from the multi-center PROCEED study
Pancreatitis is a disease continuum, starting with acute pancreatitis (AP) and, in some cases, progressing to recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP). Currently, there are no approved therapies or early diagnostic or prognostic… Continue reading
Distinct serum immune profiles define the spectrum of acute and chronic pancreatitis from the multi-center PROCEED study
Pancreatitis is a disease continuum, starting with acute pancreatitis (AP) and, in some cases, progressing to recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP). Currently, there are no approved therapies or early diagnostic or prognostic… Continue reading
Combination of mucosa-exposure device and computer-aided detection for Adenoma Detection during Colonoscopy: a randomized trial
Both Computer-aided detection (CADe)- assisted and Endocuff-assisted colonoscopy have shown to increase adenoma detection. We investigated the performance of the combination of the two tools compared to CADe-assisted colonoscopy alone to detect colorec… Continue reading
Long-term exposure to fine particulate matter and incidence of esophageal cancer: a prospective study of 0.5 million Chinese adults
Evidence is sparse and inconclusive on the association between long-term PM2.5 exposure and esophageal cancer. We aimed to assess the association of PM2.5 with esophageal cancer risk and further compared esophageal cancer risk attributable to PM2.5 exp… Continue reading
The epigenetic reader, BRD2, mediates cholangiocyte senescence via interaction with ETS1
We reported that cholangiocyte senescence, regulated by the transcription factor, ETS1, is a pathogenic feature of Primary Sclerosing Cholangitis (PSC). Furthermore, Histone 3 Lysine 27 is acetylated at senescence-associated loci. The epigenetic reader… Continue reading