Author Archives: Gastroenterology Journal
Filgotinib for the Treatment of Small Bowel Crohn’s Disease: the DIVERGENCE 1 Trial
Cannabis Could be the Missing Environmental Carcinogen Hiding in Plain View
Letter to the Editor: Drug-Induced Liver Injury with Ritonavir-Boosted Nirmatrelvir: Evidence from COVID-19 EUA Adverse Event Reporting System – Authors’ reply
Gallstones, cholecystectomy and kidney cancer: observational and Mendelian randomisation results based on large cohorts
Gallstones (cholelithiasis) constitute a major health burden with high costs related to surgical removal of the gallbladder (cholecystectomy), generally indicated for symptomatic gallstones. The association between gallstones, cholecystectomy and kidne… Continue reading
Artificial Intelligence in Pancreatic Ductal Adenocarcinoma Imaging: A Commentary on Potential Future Applications
The Long Non-coding RNA Carmn is a Critical Regulator of Gastrointestinal Smooth Muscle Contractile Function and Motility
Visceral smooth muscle cells (SMCs) are an integral component of the gastrointestinal (GI) tract that regulate GI motility. SMC contraction is regulated by post-translational signaling and the state of differentiation. Impaired SMC contraction is assoc… Continue reading
Low-dose IL-2 for the Treatment of Moderate to Severe Ulcerative Colitis
MACROPHAGE-DERIVED OSTEOPONTIN (SPP1) PROTECTS FROM NON-ALCOHOLIC STEATOHEPATITIS
Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, lobular inflammation, hepatocyte ballooning degeneration and fibrosis, all of which increase the risk of progression to end-stage liver disease. Osteopontin (OPN, SPP1) plays an import… Continue reading
Comparative Effectiveness of Anti-TNF in Combination with Low Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn’s Disease: a Pragmatic Randomized Trial
Tumor Necrosis Factor inhibitors (TNFi), including infliximab and adalimumab, are a mainstay of pediatric Crohn’s disease (PCD) therapy; however, non-response and loss of response is common. As combination therapy with methotrexate may improve response… Continue reading