Author Archives: Gastroenterology Journal

A TEAD2-driven endothelial-like program shapes basal-like differentiation and metastasis of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDA), with its highly metastatic propensity, is one of the most lethal subtypes of pancreatic cancer. Although recent large-scale transcriptomic studies have demonstrated that heterogeneous gene expressions play an ess… Continue reading

Posted in News | Comments Off on A TEAD2-driven endothelial-like program shapes basal-like differentiation and metastasis of pancreatic cancer

Lymphatic invasion of plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer

Colon cancer patients with liver metastases may be cured by surgery, but the presence of additional lung metastases often precludes curative treatment. Little is known about the processes driving lung metastasis. This study aimed to elucidate the mecha… Continue reading

Posted in News | Comments Off on Lymphatic invasion of plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer

Nausea, Vomiting, and Abdominal Distention after Atrial Fibrillation Therapy

Posted in News | Comments Off on Nausea, Vomiting, and Abdominal Distention after Atrial Fibrillation Therapy

Refining classification of cholangiocarcinoma subtypes via proteogenomic integration reveals new therapeutic prospects

Intrahepatic cholangiocarcinomas (iCCs) are characterized by their rarity, difficult diagnosis, and overall poor prognosis. The iCC molecular classification for developing precision medicine strategies was investigated. Continue reading

Posted in News | Comments Off on Refining classification of cholangiocarcinoma subtypes via proteogenomic integration reveals new therapeutic prospects

In Memorium: William Y Chey, MD, DSc, AGAF, FACG

Posted in News | Comments Off on In Memorium: William Y Chey, MD, DSc, AGAF, FACG

Host sorbitol and bacterial sorbitol utilization promote C. difficile infection in inflammatory bowel disease

Inflammatory bowel disease (IBD) is a widespread gastrointestinal inflammatory disorder with globally increasing incidence. Clostridioides difficile infection (CDI) often occurs in patients with intestinal dysbiosis, such as after antibiotic therapy. I… Continue reading

Posted in News | Comments Off on Host sorbitol and bacterial sorbitol utilization promote C. difficile infection in inflammatory bowel disease

Abdominal Pain—An Ambiguous Pancreatic Cyst

Posted in News | Comments Off on Abdominal Pain—An Ambiguous Pancreatic Cyst

Disease etiology and outcomes after atezolizumab plus bevacizumab in hepatocellular carcinoma: Post-hoc analysis of IMbrave150

Posted in News | Comments Off on Disease etiology and outcomes after atezolizumab plus bevacizumab in hepatocellular carcinoma: Post-hoc analysis of IMbrave150

Colorectal Neoplasia 10 Years or More Following Negative Colonoscopy: Time to Extend Recommended Surveillance Intervals?

Posted in News | Comments Off on Colorectal Neoplasia 10 Years or More Following Negative Colonoscopy: Time to Extend Recommended Surveillance Intervals?

Factor analysis of the Rome IV criteria for major disorders of gut-brain interaction (DGBI) globally and across geographical, sex and age groups

The Rome criteria are widely accepted for diagnosing disorders of gut-brain interaction (DGBI), but their global applicability has been debated. This study aimed to evaluate the validity of the Rome IV criteria by factor analysis globally, across geogr… Continue reading

Posted in News | Comments Off on Factor analysis of the Rome IV criteria for major disorders of gut-brain interaction (DGBI) globally and across geographical, sex and age groups