Author Archives: Gastroenterology Journal
Low Hepatitis B Core-Related Antigen Levels Correlate Higher Spontaneous Seroclearance of HBsAg in Chronic Hepatitis B Patients with High HBsAg Levels
Seroclearance of hepatitis B surface antigen (HBsAg) indicates functional cure for hepatitis B virus (HBV) infection. Low HBsAg levels can predict HBsAg seroclearance over time. However, little is known about the association between hepatitis B core-re… Continue reading
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F4/80+Ly6Chigh macrophages lead to cell plasticity and cancer initiation in colitis
Colorectal cancer (CRC) is a leading cause of cancer death with a major risk factor being chronic inflammation. Despite the link between colitis and cancer, the mechanism by which inflammation leads to CRC is not well understood. Continue reading
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Variation in testing for and incidence of celiac autoimmunity in Canada: A population-based study
Incidence of biopsy-confirmed celiac disease has increased. However, few studies have explored incidence of celiac autoimmunity based on positive serology. Continue reading
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Anti-integrin αvβ6 autoantibodies are a novel biomarker that antedate ulcerative colitis
Better biomarkers for prediction of ulcerative colitis (UC) development and prognostication are needed. Anti-integrin αvβ6 autoantibodies (anti-αvβ6) have been described in UC patients. Here, we tested for the presence of anti-αvβ6 antibodies in the pr… Continue reading
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Artificial Intelligence–Aided Colonoscopy for Characterizing and Detecting Colorectal Polyps: Required, Nice to Have, or Overhyped?
In recent years, there has been a litany of publications assessing the potential benefits of emerging artificial intelligence (AI) applications in improving select aspects of colonoscopy quality. This has especially been the case for tools to assist in… Continue reading
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Real-world implications of the AGA NAFLD Clinical Care Pathway in the US adult population
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Catechol-O-Methyltransferase Loss Drives Cell-Specific Nociceptive Signaling via the Enteric COMT/miR-155/TNF-α Axis
The etiology of abdominal pain in post-infectious, diarrhea-predominant IBS (PI-IBS-D) is unknown and few treatment options exist. Catechol-O-methyltransferase (COMT), an enzyme that inactivates and degrades biologically active catecholamines, plays an… Continue reading
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Unexpected abdominal wall varices After Split-liver Transplantation
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Continuation of Tumour Necrosis Factor Antagonists for Inflammatory Bowel Diseases During Pregnancy
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Nociceptive nerve-microbiota crosstalk during inflammation: trying to restore intestinal homeostasis
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