Author Archives: Gastroenterology Journal

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Mentoring, Education and Training: Growing Your Niche Practice

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Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation

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Non-coding aberrations in mismatch repair genes underlie a substantial part of the missing heritability in Lynch syndrome

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Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies

Necroptosis is a highly inflammatory mode of cell death that has been implicated in causing hepatic injury including steatohepatitis/NASH. However, the evidence supporting these claims has been controversial. A comprehensive, fundamental understanding … Continue reading

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Intestinal ultrasound is accurate to determine endoscopic response and remission in patients with moderate to severe ulcerative colitis: a longitudinal prospective cohort study

Intestinal ultrasound (IUS) is non-invasive, cost-effective and accurate to determine disease activity in ulcerative colitis (UC). In this study we prospectively evaluated IUS for treatment response in a longitudinal cohort by using endoscopy and histo… Continue reading

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AGA Clinical Practice Update on the Endoscopic Approach to Recurrent Acute and Chronic Pancreatitis: Expert Review

The purpose of this American Gastroenterological Association (AGA) Clinical Practice Update Expert Review is to provide practical, evidence-based guidance to clinicians regarding the role of endoscopy for recurrent acute and chronic pancreatitis. Continue reading

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COVID-19 PANDEMIC-RELATED COLORECTAL CANCER SCREENING DELAYS IMPACT UNSCREENED OLDER ADULTS THE MOST, BUT MITIGATION STRATEGIES EXIST

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Enterohepatic shunt-driven cholemia predisposes to liver cancer

Pathogenesis of hepatocellular carcinoma (HCC), which kills millions annually, is poorly understood. Identification of risk factors and modifiable determinants, and mechanistic understanding of how they impact HCC, is urgently needed. Continue reading

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Comparison of Anorectal Manometry, Rectal Balloon Expulsion Test, and Defecography for Diagnosing Defecatory Disorders

The utility of high-resolution anorectal manometry (HR-ARM) for diagnosing defecatory disorders (DDs) is unclear because healthy people may have features of dyssynergia. We aimed to identify objective diagnostic criteria for DD and to ascertain the uti… Continue reading

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