Author Archives: Gastroenterology Journal
Mentoring, Education and Training: Growing Your Niche Practice
Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation
Non-coding aberrations in mismatch repair genes underlie a substantial part of the missing heritability in Lynch syndrome
Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies
Necroptosis is a highly inflammatory mode of cell death that has been implicated in causing hepatic injury including steatohepatitis/NASH. However, the evidence supporting these claims has been controversial. A comprehensive, fundamental understanding … Continue reading
Intestinal ultrasound is accurate to determine endoscopic response and remission in patients with moderate to severe ulcerative colitis: a longitudinal prospective cohort study
Intestinal ultrasound (IUS) is non-invasive, cost-effective and accurate to determine disease activity in ulcerative colitis (UC). In this study we prospectively evaluated IUS for treatment response in a longitudinal cohort by using endoscopy and histo… Continue reading
AGA Clinical Practice Update on the Endoscopic Approach to Recurrent Acute and Chronic Pancreatitis: Expert Review
The purpose of this American Gastroenterological Association (AGA) Clinical Practice Update Expert Review is to provide practical, evidence-based guidance to clinicians regarding the role of endoscopy for recurrent acute and chronic pancreatitis. Continue reading
COVID-19 PANDEMIC-RELATED COLORECTAL CANCER SCREENING DELAYS IMPACT UNSCREENED OLDER ADULTS THE MOST, BUT MITIGATION STRATEGIES EXIST
Enterohepatic shunt-driven cholemia predisposes to liver cancer
Pathogenesis of hepatocellular carcinoma (HCC), which kills millions annually, is poorly understood. Identification of risk factors and modifiable determinants, and mechanistic understanding of how they impact HCC, is urgently needed. Continue reading
Comparison of Anorectal Manometry, Rectal Balloon Expulsion Test, and Defecography for Diagnosing Defecatory Disorders
The utility of high-resolution anorectal manometry (HR-ARM) for diagnosing defecatory disorders (DDs) is unclear because healthy people may have features of dyssynergia. We aimed to identify objective diagnostic criteria for DD and to ascertain the uti… Continue reading