Author Archives: Gastroenterology Journal
Hide and Seek – Dysplasia Camouflage in a Patient with Barrett’s Esophagus
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Rate of autoactivation determines pancreatitis phenotype in trypsinogen mutant mice
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Prolonging Survival in Advanced Esophageal Squamous Cell Carcinoma With Immune Checkpoint Inhibitors
Doki Y, Ajani A, Xu L, et al. Nivolumab combination therapy in advanced esophageal squamous-cell carcinoma. N Engl J Med 2022;386:449–462. Continue reading
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Food Insecurity in Digestive Diseases
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Can We Predict the Onset of Celiac Disease?
Celiac disease (CD) has a prevalence of nearly 1% of many countries’ populations, and its incidence appears to be increasing.1,2 The risk of CD is elevated among people with a family history,3 and therefore, testing in this population, even among asymp… Continue reading
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β-Catenin Is a Novel Target in YES-associated Protein–Driven Cholangiocarcinoma
Cholangiocarcinoma (CCA) is a heterogeneous and devastating type of cancer that develops from biliary cells in the biliary tract. Among the different subtypes of CCA, intrahepatic CCA (iCCA) accounts for 15% of primary liver tumors and has become a gro… Continue reading
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Arid1a: A Gatekeeper in the Development of Pancreatic Cancer From a Rare Precursor Lesion
Pancreatic intraepithelial neoplasia, intraductal pancreatic mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) are the common precursor lesions of pancreatic cancer. The gene abnormalities of those precursor lesions are characterized by Kras… Continue reading
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Mucus Sialylation Maintains the Peace in Intestinal Host Microbe Relations
Yao Y, Kim G, Shafe S, et al. Mucus sialylation determines intestinal host-commensal homeostasis. Cell 2022;185:1172–1188. Continue reading
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Controversy of Preoperative Exposure to Tumor Necrosis Factor Inhibitors in Surgical and Infectious Complications of Inflammatory Bowel Disease
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Association between Metabolic Syndrome and the Risk of Colorectal Cancer Diagnosed before 50 years According to Tumor Location
The increasing prevalence of obesity at younger ages is concurrent with an increased earlier-onset colorectal cancer (CRC) ( Continue reading
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