Author Archives: Gastroenterology Journal

Toll Like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-Induced Gastric Metaplasias

A subset of MDSCs that express murine Schlafen4 (SLFN4) or its human ortholog SLFN12L polarize in the Helicobacter-inflamed stomach coincident with intestinal or spasmolytic polypeptide-expressing metaplasia (SPEM). We propose that individuals with a m… Continue reading

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Gastroenterology: A New Editorial Team Coming to You From Around the World

We assume leadership of Gastroenterology with a blend of humility, trepidation, and excitement. There have been many eminent Editors-in-Chief of Gastroenterology, including our immediate predecessors, Richard M. Peek, Jr, MD, AGAF, and Douglas A. Corle… Continue reading

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Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer

The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis syndr… Continue reading

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Prediction models for celiac disease development in children from high-risk families: Data from the PreventCD cohort

Screening for celiac disease (CD) is recommended in children with affected first-degree relatives (FDR). However, the frequency of screening and at what age remain unknown. Aims:to detect variables influencing the risk of CD-development and develop and… Continue reading

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A Distinct and Potentially Deadly Cause of Gastric Polyposis

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When neurology meets gastroenterology: an unusual case of ulcerative colitis

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Sudden fatal abdominal pain in an old man with chronic constipation

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Accurate Non-Endoscopic Detection of Esophageal Squamous Cell Carcinoma (ESCC) Using Methylated DNA Biomarkers

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Loss of Arid1a and Pten in pancreatic ductal cells induces intraductal tubulopapillary neoplasm via the YAP/TAZ pathway

Pancreatic ductal adenocarcinoma (PDAC) arises from several types of premalignant lesions, including intraductal tubulopapillary neoplasm (ITPN); however, the molecular pathogenesis of ITPN remains unknown. Continue reading

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Factors Associated with Geographic Disparities in Gastrointestinal Cancer Mortality in the United States

Significant geographic variability in gastrointestinal (GI) cancer-related death has been reported in the United States. We aimed to evaluate both modifiable and non-modifiable factors associated with inter-county differences in mortality from GI cancer. Continue reading

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