Author Archives: Hartmut Jaeschke

Mechanisms of Acetaminophen Hepatotoxicity: Do We Need JNK for Cell Death?

During the last decade, c-jun N-terminal kinase (Jnk) emerged as central player in the pathophysiology of acetaminophen (APAP)-induced liver injury, especially in mice.1,2 Jnk activation and translocation of phosphorylated-Jnk (p-Jnk) to mitochondria w… Continue reading

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