Author Archives: Ja Hyun Koo, Hyo Ju Lee, Won Kim, Sang Geon Kim

Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2

Posted on October 2, 2015 by Ja Hyun Koo, Hyo Ju Lee, Won Kim, Sang Geon Kim

Endoplasmic reticulum (ER) stress has been implicated in a variety of diseases. Hepatic stellate cells (HSCs) contribute to the development of liver fibrosis. Information on the link between ER stress and HSC activation is scarce. We investigated the e… Continue reading →

Posted in News | Comments Off on Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-Mediated Degradation of HNRNPA1 and Up-regulation of SMAD2