Author Archives: Jittima Weerachayaphorn, Maria Jimena Amaya, Carlo Spirli, Piyachat Chansela, Kisha A. Mitchell-Richards, Meenakshisundaram Ananthanarayanan, Michael H. Nathanson
Nuclear Factor, Erythroid 2-Like 2 Regulates Expression of Type 3 Inositol 1,4,5-Trisphosphate Receptor and Calcium Signaling in Cholangiocytes
Most cholestatic disorders are caused by defects in cholangiocytes. The type 3 isoform of the inositol 1,4,5-trisphosphate receptor (ITPR3) is the most abundant intracellular calcium release channel in cholangiocytes. ITPR3 is required for bicarbonate … Continue reading
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