Author Archives: Khalidur Rahman, Chirayu Desai, Smita S. Iyer, Natalie E. Thorn, Pradeep Kumar, Yunshan Liu, Tekla Smith, Andrew S. Neish, Hongliang Li, Shiyun Tan, Pengbo Wu, Xiaoxiong Liu, Yuanjie Yu, Alton B. Farris, Asma Nusrat, Charles A. Parkos, Frank A. Anani

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

Posted on June 21, 2016 by Khalidur Rahman, Chirayu Desai, Smita S. Iyer, Natalie E. Thorn, Pradeep Kumar, Yunshan Liu, Tekla Smith, Andrew S. Neish, Hongliang Li, Shiyun Tan, Pengbo Wu, Xiaoxiong Liu, Yuanjie Yu, Alton B. Farris, Asma Nusrat, Charles A. Parkos, Frank A. Anani

There is evidence from clinical studies that compromised intestinal epithelial permeability contributes to the development of nonalcoholic steatohepatitis (NASH), but the exact mechanisms are not clear. Mice with disruption of the gene (F11r) encoding … Continue reading →

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