Author Archives: Kirk Bergstrom, Xiaowei Liu, Yiming Zhao, Nan Gao, Qian Wu, Kai Song, Yi Cui, Yun Li, J. Michael McDaniel, Samuel McGee, Weichang Chen, Mark M. Huycke, Courtney W. Houchen, Lauren A. Zenewicz, Christopher M. West, Hong Chen, Jonathan Braun, Jianxin F
Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice
Core 1– and core 3–derived mucin-type O-linked oligosaccharides (O-glycans) are major components of the colonic mucus layer. Defective forms of colonic O-glycans, such as the Thomsen-nouveau (Tn) antigen, frequently are observed in patients with ul… Continue reading
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