Author Archives: Kyle C. Roche, Adam D. Gracz, Xiao Fu Liu, Victoria Newton, Haruhiko Akiyama, Scott T. Magness

SOX9 Maintains Reserve Stem Cells and Preserves Radio-resistance in Mouse Small Intestine

Posted on July 10, 2015 by Kyle C. Roche, Adam D. Gracz, Xiao Fu Liu, Victoria Newton, Haruhiko Akiyama, Scott T. Magness

Reserve intestinal stem cells (rISCs) mediate epithelial regeneration following tissue damage. Unlike active intestinal stem cells (aISCs), rISCs slowly cycle under homeostatic conditions, allowing for their identification with label retention assays. … Continue reading →

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