Author Archives: Petra Hirsova, Samar H. Ibrahim, Anuradha Krishnan, Vikas K. Verma, Steven F. Bronk, Nathan W. Werneburg, Michael R. Charlton, Vijay H. Shah, Harmeet Malhi, Gregory J. Gores

Lipid-induced Signaling Causes Release of Inflammatory Extracellular Vesicles from Hepatocytes

Posted on January 4, 2016 by Petra Hirsova, Samar H. Ibrahim, Anuradha Krishnan, Vikas K. Verma, Steven F. Bronk, Nathan W. Werneburg, Michael R. Charlton, Vijay H. Shah, Harmeet Malhi, Gregory J. Gores

Hepatocyte cellular dysfunction and death induced by lipids, and macrophage-associated inflammation are characteristics of nonalcoholic steatohepatitis (NASH). The fatty acid palmitate can activate death receptor 5 (DR5) on hepatocytes, leading to thei… Continue reading →

Posted in News | Comments Off on Lipid-induced Signaling Causes Release of Inflammatory Extracellular Vesicles from Hepatocytes

Lipid-induced Signaling Causes Release of Inflammatory Extracellular Vesicles from Hepatocytes

Posted on January 4, 2016 by Petra Hirsova, Samar H. Ibrahim, Anuradha Krishnan, Vikas K. Verma, Steven F. Bronk, Nathan W. Werneburg, Michael R. Charlton, Vijay H. Shah, Harmeet Malhi, Gregory J. Gores

Hepatocyte cellular dysfunction and death induced by lipids, and macrophage-associated inflammation are characteristics of nonalcoholic steatohepatitis (NASH). The fatty acid palmitate can activate death receptor 5 (DR5) on hepatocytes, leading to thei… Continue reading →

Posted in News | Comments Off on Lipid-induced Signaling Causes Release of Inflammatory Extracellular Vesicles from Hepatocytes