Author Archives: Stacey A. Cohen, Emily H. Turner, Mallory B. Beightol, Angela Jacobson, Ted A. Gooley, Stephen J. Salipante, Sigurdis Haraldsdottir, Christina Smith, Sheena Scroggins, Jonathan F. Tait, William M. Grady, Edward H. Lin, David E. Cohn, Paul J. Goodfell

Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors with 2 or More Somatic Mutations in Mismatch Repair Genes

Posted on June 11, 2016 by Stacey A. Cohen, Emily H. Turner, Mallory B. Beightol, Angela Jacobson, Ted A. Gooley, Stephen J. Salipante, Sigurdis Haraldsdottir, Christina Smith, Sheena Scroggins, Jonathan F. Tait, William M. Grady, Edward H. Lin, David E. Cohn, Paul J. Goodfell

Some colorectal and endometrial tumors with microsatellite instability not attributable to MLH1 hypermethylation or germline mutations contain 2 or more somatic mutations in genes encoding mismatch repair (MMR) proteins. We sought to define the molecul… Continue reading →

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