Author Archives: Takahiro Kodama, Emilie A. Bard-Chapeau, Justin Y. Newberg, Michiko Kodama, Roberto Rangel, Kosuke Yoshihara, Jerrold M. Ward, Nancy A. Jenkins, Neal G. Copeland

Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma

High-throughput sequencing technologies have identified thousands of infrequently mutated genes in hepatocellular carcinomas (HCCs). However, high intratumor and intertumor heterogeneity, combined with large numbers of passenger mutations, have made it… Continue reading

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