Category Archives: News

Letter to the Editor Response

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Genetic Variation in Sugar Metabolism Confers a Protective Metabolic Profile

Dietary sugar intake is associated with various metabolic disorders. A study by Anderson et al describes an arctic population whose genetic variation in sucrase-isomaltase (SI), an intestinal sucrose breakdown enzyme, confers a healthier anthropometric… Continue reading

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Achieving Health Equity through Digestive Diseases Research and Scientific Workforce Diversity

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Off-the-shelf PSCA-directed chimeric antigen receptor natural killer cell therapy to treat pancreatic cancer

Pancreatic cancer (PC) is the third leading cause of cancer-related death with a 5-year survival rate of approximately 10%. It typically presents as a late-stage incurable cancer and chemotherapy provides modest benefit. Here, we demonstrate the feasib… Continue reading

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Early life: an important window of susceptibility for colorectal cancer

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Design of clinical trials for mild-to-moderate ulcerative colitis

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“Broadening our understanding of the immune landscape in Lynch syndrome”

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The insightful clarification of miR-144 mediated metabolic dysfunction

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Colorectal cancer screening in IBD – can characterization of GI microbiome signatures enhance neoplasia detection?

Current non-invasive CRC screening methods are not optimized for persons with IBD, requiring patients to undergo frequent interval screening via colonoscopy. Although colonoscopy-based screening reduces CRC incidence in IBD patients, rates of interval … Continue reading

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Liver Mass: Thinking out-of-the box

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